| Date | Location | Result | |
| 12-18-21 | Mobile, Ala. | Liberty 56, Eastern Michigan 20 | Box score |
| 11-27-21 | Lynchburg, Va. | Army West Point 31, Liberty 16 | Box score |
| 11-20-21 | Lynchburg, Va. | Louisiana 42, Liberty 14 | Box score |
| 11-06-21 | Oxford, Miss. | Ole Miss 27, Liberty 14 | Box score |
| 10-30-21 | Lynchburg, Va. | Liberty 62, UMass 17 | Box score |
| 10-23-21 | Denton, Texas | Liberty 35, North Texas 26 | Box score |
| 10-16-21 | Monroe, La. | ULM 31, Liberty 28 | Box score |
| 10-09-21 | Lynchburg, Va. | Liberty 41, Middle Tennessee 13 | Box score |
| 10-02-21 | Birmingham, Ala. | Liberty 36, UAB 12 | Box score |
| 09-24-21 | Syracuse, N.Y. | Syracuse 24, Liberty 21 | Box score |
| 09-18-21 | Lynchburg, Va. | Liberty 45, Old Dominion 17 | Box score |
| 09-11-21 | Troy, Ala. | Liberty 21, Troy 13 | Box score |
| 09-04-21 | Lynchburg, Va. | Liberty 48, Campbell 7 | Box score |